Mobilizing the Immune SystemA clinical-stage biopharmaceutical company leveraging from its multiple drug development platforms to treat patients with inflammatory diseases, viral infections, and cancer.
Fighting Inflammatory DiseasesAbivax’s lead candidate ABX464, a potent anti-inflammatory agent, is entering a Phase 2b clinical trial for its potential to bring clinical benefit to patients with ulcerative colitis, and potentially other inflammatory indications.
Developing a Functional Cure for HIVABX464 is a Phase 2 candidate designed to functionally cure HIV by reducing the viral reservoir and is the first ever drug candidate to demonstrate this reduction in patients.
Tackling CancerA small molecule agonist of invariant Natural Killer T-Cells (iNKT) to be tested in Phase 1/2 clinical trial for treatment of hepatocellular carcinoma (HCC).
Abivax is developing therapies that stimulate the body’s natural immune system machinery. A clinical-stage company, Abivax leverages its immune enhancing and antiviral platforms to develop drug candidates to treat ulcerative colitis, HIV, and liver cancer.
Its lead clinical candidate, ABX464, has demonstrated the potential to address indications in two disease areas: treatment of inflammation in ulcerative colitis and reduction of the viral reservoir in HIV.
Abivax recently presented impressive results from its ABX464 maintenance study in ulcerative colitis at the United European Gastroenterology Conference, UEG Week 2019, in Barcelona, Spain on October 21, 2019. This data showed that impressive efficacy initially reported at 8 weeks after completion of the induction study is durable or improving at 12 months with ABX464. You can see documentation from these presentations here:
Abivax recently presented impressive 9-month interim extension data from studies of ABX464 in ulcerative colitis during an oral presentation at DDW 2019, demonstrating a continued duration of beneficial effect in patients treated up to 11 months with ABX464 (for patients who received ABX464 during the placebo controlled 8 weeks induction study). View the conference presentation, here:
On Thursday March 21, 2019, Abivax hosted a webcast of their KOL lunch, in which Prof. Ian McGowan, MB ChB DPhil MD FRCP, from the University of Miami Miller School of Medicine discussed Abivax’s recently presented results from its Phase 2a extension study of ABX464 in ulcerative colitis. A recording of the webcast can be accessed via the following link:
With three products in clinical trials and four products in Research and Preclinical development, Abivax’s pipeline is strong and diversified, addressing many unmet needs.
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Abivax SA has been listed on the Paris stock exchange since June 26, 2015.